Deep Tech for Human and Planetary Health

SOSV is a multi-stage investment firm and one of the world's most active deep tech venture capital firms, investing at the pre-seed stage. The firm is dedicated to supporting startups that address critical challenges for human and planetary health through groundbreaking technological innovation. With deeply resourced locations in New York, Newark, and San Francisco, SOSV provides a unique ecosystem for founders to accelerate their ventures.

Mission and Values

SOSV's core mission is to help startups go "further, faster" by providing not just capital but also extensive operational support, lab space, and a vast network of investors and mentors. The firm is deeply committed to fostering innovation in deep tech, recognizing its potential to create significant positive impact on the world. This commitment is evidenced by its focus on areas like biotech, hardware, and sustainable technologies, as well as the high percentage of founders with PhDs (44% from 2021-2025) within its portfolio.

Program Structure and Timeline

While SOSV is an investment firm, it operates several renowned accelerator programs, including HAX for hardware and IndieBio for biotech. These programs are designed to provide intensive support to early-stage deep tech companies. The firm's approach involves hands-on engagement, leveraging its 85,000 square feet of lab and office space to facilitate rapid development and prototyping. Although specific program durations are not explicitly stated, the emphasis on acceleration suggests a structured, time-bound program designed for rapid progress.

Mentorship and Network

SOSV boasts an impressive network, including 2,700 co-investors and a broader network of 7,500 investors. This extensive network provides portfolio companies with unparalleled access to follow-on funding and strategic partnerships. The firm also emphasizes mentorship, connecting founders with experienced entrepreneurs, industry experts, and scientists who can guide them through the technical and business challenges of deep tech. The success stories of companies like unspun, Ten63, and NotCo highlight the effectiveness of this mentorship and network in scaling innovative solutions.

Investment Terms

As a venture capital firm, SOSV provides pre-seed investment to its portfolio companies. While specific investment amounts and equity terms are not detailed on the provided website content, the firm's role as a venture capital investor implies taking equity in exchange for funding and program participation. The significant amount raised by portfolio companies ($7.5 billion from 2021-2025) underscores the substantial financial backing and subsequent investment rounds secured by SOSV-backed startups.

What Makes it Unique

SOSV's uniqueness lies in its deep specialization in deep tech, combined with its hands-on, accelerator-like approach. Unlike traditional VCs, SOSV offers dedicated lab and office spaces, tailored programs like HAX and IndieBio (now integrated into SOSV NY & SOSV SF), and a strong emphasis on scientific and engineering rigor. The firm's focus on "human and planetary health" provides a clear mission-driven framework, attracting founders who are not only innovative but also aiming for significant global impact. The firm's ability to turn academic projects into successful ventures, as seen with Ten63, further distinguishes its model.

Notable Outcomes

SOSV has an impressive track record, with over 800 portfolio companies that have collectively raised $7.5 billion between 2021 and 2025. Notable alumni include unspun, which aims to eliminate 1% of global carbon emissions with its weaving machines; Ten63, developing an AI platform for "undruggable" cancers; NotCo, leveraging AI for plant-based foods; Novoloop, upcycling plastics; Prolific Machines, working on affordable cultured meat; OpenTrons, a billion-dollar open-source laboratory robot company; and Upside Foods, a leader in cultivated meat. These examples showcase the breadth and impact of SOSV's portfolio.

What Participants Can Expect Day-to-Day

Founders participating in SOSV's programs can expect an intense, supportive, and resource-rich environment. This includes access to state-of-the-art lab and office facilities, direct engagement with a team of experts, and continuous opportunities for mentorship and networking. The focus is on rapid iteration, problem-solving, and scaling, with the ultimate goal of transforming deep tech innovations into viable, impactful businesses.